“He Yuan Li Ji” was established as a joint venture between He Yuan Bio (stock code: 688238) and Li Ji Bio, with its core business centered on the “Li Ji Bio” and “Life-ilab” reagent brands.

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The effects of exosome-depleted fetal bovine serum (the price of serum without exosomes)

Publication date:2024-12-26
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Fetal bovine serum (FBS) is an indispensable component of complete cell culture media, as it provides essential nutrients and growth factors that support cell proliferation. However, conventional FBS contains high levels of bovine‑derived exosomes, which can interfere with studies on exosome secretion by cultured tissues or cells, thereby compromising experimental outcomes. In contrast, the exosome‑free FBS independently developed by HeYuan Li Ji is produced from premium‑grade FBS and subjected to ultracentrifugation at 100,000 × g, 4°C, for 10 hours, followed by sterile filtration to remove endogenous exosomes. This optimized processing effectively minimizes background signals arising from exogenous contaminants, making it well suited for exosome isolation experiments and related research in cell culture.

The effect of exosome-containing fetal bovine serum

✔ Reduce Exogenous background signal Interference;

✔ Improve cell culture efficiency;

✔ Remove more than 97% of endogenous exosomes from serum;

✔ Suitable for exosome isolation experiments or related research in cell culture.

The price of exosome-free serum (based on Li Ji Bio For example)

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Product Name: Exosome-Free Fetal Bovine Serum

Product SKU: AC03L953

Product Specification: 50 mL

Product Price: 2,200

Applications of exosome-containing fetal bovine serum

Exosomes can be associated with virtually any disease, making them an innovative research hotspot for biomarker discovery, elucidation of disease mechanisms, and drug development. To date, more than 200 clinical trials have investigated exosomes, primarily focusing on various cancers, skin injuries, anti‑aging, polycystic ovary syndrome, dry eye syndrome, and related areas.

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