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How should serum be thawed in a controlled, stepwise manner?
Publication date:2026-10-29
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Procedural thawing of serum ensures the stability of serum product quality and prevents excessive precipitation of proteins or other impurities due to large temperature differentials. The procedure involves placing frozen serum in a 4°C refrigerator prior to experimentation and, during thawing, gently inverting the container every hour to promote uniform temperature and composition, thereby minimizing precipitate formation until complete thawing is achieved; the serum is then transferred to room‑temperature conditions for use.
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