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Puromycin solution (1 mg/mL)
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AB12L24210*1mL398
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Product Description
Puromycin (PM) is a protein synthesis inhibitor that possesses a structure similar to the terminal end of tRNA molecules, enabling it to bind to amino acids. It can substitute for aminoacylated tRNA by binding to the A site of the ribosome and become incorporated into the growing polypeptide chain. Although puromycin can bind to the A site, it cannot participate in subsequent reactions, thereby terminating protein synthesis and releasing an immature polypeptide with puromycin attached at its C‑terminus. The molecular weight of puromycin is 544.43 g/mol, and its CAS number is 53‑79‑2.
This product is prepared by dissolving high-purity raw materials in deionized water; if necessary, it should be filtered through an organic membrane prior to use in cell culture. The puromycin solution (1 mg/mL) has a molar concentration of 1.84 mM, and the typical working concentration ranges from 10 to 100 μM.
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Product Name
Item number
Specifications
Puromycin solution (1 mg/mL)
AB12L242
10*1 mL
Transportation and Storage
Blue ice transport. Store at −20°C; shelf life: 12 months.
Related Product Recommendations
X-gal (20 mg/mL) (Item No.: AN60L178)
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This product is intended solely for scientific research and must not be used for clinical diagnosis, treatment, or any other purposes.
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